- This disambiguation page lists articles associated with the same title. If an internal link led you here, you may wish to change the link to point directly to the intended article.
- Samuel Anders, a Battlestar Galactica (2003) character
- Samuel Seaborn, a The West Wing character
- Samuel Vimes, a Discworld character
- Samuel Wilson, a Marvel Comics character
- Sam Winchester, a Supernatural character
- Michael Samuelle, a La Femme Nikita character