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Leyla Harrison was an X-Files fan and popular fanfic writer during the height of the series' popularity, who was well-known on the message boards and Usenet groups. She passed away in February 2001. In May 2001, in the episode Alone, Agent Leyla Harrison was introduced as a tribute to her. In 2002, Agent Harrison returned in the ninth season episode Scary Monsters.
In 2001, a fan named Leyla Harrison, a highly talented writer of X-Files fan fiction, died from melanoma after a long struggle with the disease. The Scully character had a lengthy cancer storyline on the show (for which Gillian Anderson won the Emmy that year) around the same time as Leyla was first diagnosed. Many of Leyla's stories, but certainly not all, were Scully point-of-view narratives as the character came to terms with the diagnosis and what the cancer was doing to her life. These stories are beautifully told, and I'm sure full of Leyla's own firsthand experiences, which makes them even more poignant.
Just after she died and right before David Duchovny left the show for good, the episode "Alone" was aired, featuring Special Agent Leyla Harrison, who was named in her honor as a tribute. Appropriately, the Agent Harrison character was full of X-Files trivia and obscure references, just like a real-life fan of the show.,  
- A tribute page for Leyla Harrison
- "When a popular X-Files fanfiction writer was battling a recurrence o f melanoma, an online friend sent a letter to co-executive producer Frank Spotnitz, asking him to write to her. Spotnitz did. When he learned this year that she had died, hewas preparing to write an episode about a young FBI agent who knows and loves everything about the X-Files and Agents Mulder and Scully. "I hadn't decided if it was a man or awoman yet. But when she passed away, it felt like too perfect a way to paytribute to her," he said of his decision to name the character Special Agent Leyla Harrison, after the woman." -- from a 2001 article in The Washington Post called The E-Files